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S0191
Sigma
Sonic Hedgehog Peptide from mouse
≥97% (SDS-PAGE), recombinant, expressed in Escherichia coli, Fused to a histidine tag at the C-terminus, lyophilized powder
| Synonym: | Shh |
| MDL number: | MFCD03792594 |
Description
| Other Notes | N-terminal peptide encoding amino acid residues 25-198. |
| Physical form | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 7.4, containing 5% trehalose and 50 μg of bovine serum albumin per 1 μg of cytokine. |
| Biochem/physiol Actions | Cell signaling peptide involved in embryonic morphogenic development of several tissues including Hensen's node, the notochord, and the neural tube. |
Properties
| recombinant | expressed in Escherichia coli |
| assay | ≥97% (SDS-PAGE) |
| form | lyophilized powder |
| mol wt | predicted mol wt 20 kDa |
| Gene Information | mouse ... Shh(20423) |
| storage temp. | −20°C |
Safety
| Hazard Codes | T |
| Risk Statements | 23/24/25-41 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 2 |
References
| reference | Liu, W., et al., Sonic hedgehog regulates otic capsule chondrogenesis and inner ear development in the mouse embryo. Dev. Biol. 248, 240-250, (2002) |
| Pola, R., et al., The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors. Nat. Med. 7, 706-711, (2001) | |
| Goetz, J.A., et al., Sonic Hedgehog as a mediator of long-range signaling. Bioessays 24, 157-165, (2002) |
